This cycle is structured so that the individual substances complement each other and create the highest possible level of synergy, while also considering the minimisation of potential negatives. The cycle lasts 16 weeks, and then on day 140 the PCT should begin, or you have the option to continue for another month on testosterone alone and only then start the PCT. This is a more reasonable choice than discontinuing everything at once and thus facing a significant androgen crash = rapid muscle loss, depression, fatigue.
Let’s describe the cycle in more detail. Throughout the entire cycle, these 3 injectable substances are used together on the same day:
1. Testosterone Enanthate or Cypionate
It is the foundation of the cycle, and its dose can be adjusted according to your experience, ideally within a reasonable range of 400 to 600 mg per week.
You choose the ester according to your own preference; it does not matter whether it is Enanthate or Cypionate.
2. Nandrolone Decanoate
Its dose is set at 250 mg per week, and you can of course adjust it higher, again based on your own experience, ideally within a reasonable range of 250 to 500 mg per week.
Testosterone and Nandrolone in this cycle are the most anabolic substances, which will primarily ensure hypertrophy.
Nandrolone increases the breakdown of dopamine, which negatively affects cognition, learning, memory, and many of you may experience demotivation, apathy, lack of drive, emotional fluctuations during its use. For this reason, a lower dose of Trenbolone is added to Nandrolone, as Trenbolone increases dopaminergic activity — meaning it acts opposite to Nandrolone, and thus can to a certain extent eliminate, in most cases, demotivation, apathy, and lack of drive.
Nandrolone Decanoate must be discontinued earlier, just as you can see in the cycle, because Decanoate is a longer ester than Enanthate and therefore stays in the system naturally a bit longer. So, in order to prevent Nandrolone from negatively affecting the PCT, it must be stopped earlier.
3. Trenbolone Enanthate
Its dose is set quite low, at 150 mg per week, which is fully sufficient for its purpose ⇒ eliminating the negative dopaminergic effects arising from the use of Nandrolone. I would not increase the dose unnecessarily; it is not needed.
At the same time, even such a low dose is enough for Trenbolone to increase the utilisation of IGF-1, because it is the only AAS that dramatically increases muscle sensitivity to systemic IGF-1, thanks to more efficient utilisation of IGF-1 isoforms (IGF-1Ea, IGF-1Ec, MGF) found in muscles. By itself, it increases IGF-1 levels only very little, but when used together with testosterone (an aromatising compound), a strong synergistic effect occurs. Both testosterone and Nandrolone in this cycle will increase IGF-1 levels, and Trenbolone will ensure the maximum utilisation of systemic IGF-1.
Additional substances in the cycle are:
4. Oxandrolone:
While the full effect of Testosterone, Nandrolone and Trenbolone applied every fourth day develops, it will take quite a long time. Stable levels in the blood can be observed after approximately:
A. Testosterone Enanthate = after about 4 weeks
B. Nandrolone Decanoate = after about 6 weeks
C. Trenbolone Enanthate = after about 4 weeks
And therefore, so that you do not wait too long for the first noticeable effects and so that the cycle is enjoyable from the beginning, Oxandrolone is included in the cycle for the first 4 weeks at a daily dose of 40 mg. You can again adjust the dose within the range of 30 to 50 mg daily. The duration can also be extended to 5 or 6 weeks, depending on how you decide. Instead of Oxandrolone, you can of course use Stanozolol, Methyldrostanolone, or Turinabol — it’s up to you.
5. Pitavastatin:
It is used throughout the entire cycle with the goal of improving cholesterol levels as much as possible. Its dose is set low, only 2 mg daily; for those of you who are sensitive to cholesterol and quickly experience negative changes during AAS use, you can choose 4 mg daily. Do not forget that Oxandrolone, Stanozolol, and Methyldrostanolone belong among the substances that strongly negatively affect cholesterol, and Turinabol is not much of an exception either!
6. BPC-157:
It is used in the cycle to increase the regeneration of various tendon or muscle injuries. It is especially suitable during the use of Oxandrolone, when muscle strength increases rapidly for most of you, and at that time you are most prone to injuries. At the same time, many of you already know that during the use of oral compounds, and later as well, reflux is common, which is quite unpleasant, and BPC can reduce this effect to some extent, significantly improving the quality of the cycle.
BPC-157 is used in the cycle in two periods because long-term studies still do not exist, and therefore it is better to use it only for a short time, then discontinue, and then use again.
BPC-157 is not recommended to be taken before training, because the massive increase in blood flow that it causes is counterproductive for injury recovery. It is similar to doing rehabilitation for an injury while applying a heated pad to it at the same time. This must not be done because of the excessive swelling/blood flow. It also should not be applied shortly after training, because it has a strong anti-inflammatory effect, and it would likely be undesirable to disrupt the natural post-training inflammatory processes. Simply put, taking BPC-157 is best done in the morning after waking up and in the evening before going to bed. Not before training and not after training.
7. HCG:
HCG is used throughout the entire cycle at a dose of 500 IU, but you may freely lower it to 250 IU, depending on how you feel, because even 250 IU should be fully sufficient.
Most of you greatly underestimate the use of HCG during the cycle because you perceive it, due to lack of knowledge, only as a substance that allows you to have children — which frankly sounds very funny. HCG is not about having children, nor does it prevent testicular atrophy. HCG is an LH analogue, which forces your testicles to produce intratesticular testosterone! This means your testicles will not be in an “off” state during the cycle but will continue producing, which will make PCT significantly easier.
At the same time, during an AAS cycle, the production of DHEA and pregnenolone decreases, and HCG increases their production! A decrease in pregnenolone leads to worsened mood, reduced stress resilience, anxiety, irritability, emotional instability, weaker memory, and mental fatigue — and yes, that is exactly why you often feel like garbage during the cycle. And what about DHEA? Again, low DHEA is connected with fatigue, depression, low motivation, weakened immunity, etc. And yes, this is another reason why you often feel like a “beaten dog” in the cycle.
I also mentioned that HCG does not prevent atrophy — of course it does not, because it acts only on Leydig cell receptors, which form about 10% of testicular volume, while the remaining testicular volume consists of Sertoli cell receptors, which respond to FSH — and FSH will also be suppressed to a minimum during the cycle due to AAS use. Therefore atrophy simply will happen. If you wanted to prevent testicular atrophy, you would have to use HMG (LH + FSH) during the cycle, which would stimulate sperm production and keep you fertile throughout the cycle — and only now can we, “dear children”, talk about babies.
8. Anastrozole:
The level of E2 must always be monitored in the cycle. Most of you — and I dare say the vast majority — focus only on gynecomastia during an AAS cycle, which is one of the most foolish symptoms you can focus on. Because even with elevated E2, you might not have any problem with gynecomastia; each of us has a different number of receptors in breast tissue, arranged differently and with different sensitivity.
Long-term elevated and uncontrolled E2 brings much more serious issues, such as:
A. Long-term elevated E2 increases the risk of thrombosis (blood clots)
B. Long-term elevated E2 increases prolactin, which lowers libido and worsens erections
C. Long-term elevated E2 causes mood swings, anxiety, and depression
D. Long-term elevated E2 causes increased fat accumulation in the hips and chest
E. Long-term elevated E2 in men increases cancer risk by more than 30% (prostate), etc.
Therefore throughout the entire cycle it is necessary to control estrogen levels using an aromatase inhibitor. The cycle includes Anastrozole, but you may also use Exemestane at 10 mg every day or every other day. And yes, this is necessary also because Nandrolone and Trenbolone accelerate the aromatization of Testosterone into E2.
Those of you who would like to go more in a bulking direction can replace Oxandrolone with Methandienone or Oxymetholone. Below you can see the cycle with Oxymetholone. But what is important with this variant? You must have SERMs on hand, meaning an anti-estrogen, even though you will be using an aromatase inhibitor. Most of you again do not understand how an aromatase inhibitor works, because it only eliminates the creation of E2 in men by about ±30 to 40%, which means E2 will still be produced! And no, it is not true that aromatase inhibitors can reduce E2 levels in men by 70–80–90%. These results come from female studies, not male ones! In men, aromatase inhibitors have a weaker effect than in women! That’s why it is necessary to have an anti-estrogen on hand, either Tamoxifen or Raloxifene. Why? Because Methandienone converts into a very strong type of estrogen — methylestradiol — which is 2 to 5 times more aggressive than regular E2. Oxymetholone does not convert to E2, so technically an inhibitor is not effective with it, but by itself it is E2-mimetic, meaning it has its own estrogenic activity, and here only SERMs can help.
So if you choose this cycle where you will be using Methandienone or Oxymetholone and you start to feel significantly increased sensitivity in the chest area (nipples), it is better to take 10–20 mg of Tamoxifen daily or 30–60 mg of Raloxifene daily.
What dose should you choose? For Methandienone, 30–40 mg daily, and for Oxymetholone, 50–100 mg daily should be enough. The duration of use is also 4–6 weeks.
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