Clenbuterol, Sibutramine, T3, Cardarine
I have put together several cycles for you that will significantly help you with reducing excess fat from your body. To begin with, I emphasize that the most important factor in cycles focused on fat loss is diet, and—if you have the possibility and capacity—also substantial cardio activity. These cycles include various substances such as Clenbuterol, Sibutramine, T3, Cardarine, each of which has its own specific purpose. We will gradually write something about each of them; let’s also take a look directly at the cycles.
1. Eight-week cycle using Sibutramine, Clenbuterol, and Cardarine
This is a cycle without the use of AAS, where it will not be necessary to control E2 levels or to start PCT after discontinuing AAS. It is therefore a suitable option for those who do not want to use AAS. Let’s go over the basic information about the substances used in this cycle:
Sibutramine
It is an anorectic, an appetite-suppressing drug intended for the treatment of obesity, which increases the levels of neurotransmitters in the brain, leading to:
• Reduced appetite
• Faster feeling of satiety
• Slight increase in metabolism and a mild stimulating effect
This drug is no longer used in medicine today; it was withdrawn from the market. Why? Because it was prescribed to people with a BMI higher than 30%, and these people used it long-term — from 6 months up to 4 years. These were mostly patients aged 55 and older who, even before using Sibutramine, already suffered from high blood pressure, diabetes, or dyslipidemia ⇒ these are individuals with an increased risk of cardiovascular disease, and in these people an increased rate of negative effects appeared, by 2–4% compared to placebo (heart attack, significant increase in blood pressure, arrhythmias, strokes). Since this drug was intended primarily for them, it could not be kept on the market. In younger people with lower BMI, these negative effects did not occur. Regulatory authorities must assess the safety of a drug for the population as a whole, unfortunately — and especially for the target group (severely obese patients), and in them the risk–benefit ratio was simply unfavorable. Therefore, if this drug is used by younger people (up to 50 years of age) with mild obesity, and used short-term for 1–3 months, it is essentially a very safe drug.
Sibutramine was taken at 10 to 20 mg daily. Most often it was always the 10 mg dose, and if no significant change occurred after 4 weeks, the dose was increased to 15 mg, and later, in some specific patients, the dose was increased over time to 20 mg daily. Today, Sibutramine is misused exactly at these same doses. In the cycle you see the dose of 10 mg daily, which later increases to 15 mg daily. The entire dose is always taken at once in the morning after waking up. Sibutramine can be used safely for 1–3 months; in this cycle it is used for 2 months — the first 4 weeks at 10 mg and the next 4 weeks at 15 mg daily.
Clenbuterol
It is probably one of the most well-known substances that people misuse in fat-burning cycles. Clenbuterol is a beta-2-adrenergic agonist similar (just similar) to Salbutamol. When using Clenbuterol for the first time, you begin gradually with a pyramid scheme, as follows:
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Monday = 20 mcg in the morning + 20 mcg in the afternoon
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Tuesday = 20 mcg in the morning + 20 mcg in the afternoon
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Wednesday = 30 mcg in the morning + 30 mcg in the afternoon
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Thursday = 30 mcg in the morning + 30 mcg in the afternoon
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Friday = 40 mcg in the morning + 40 mcg in the afternoon
And this dose remains the same and is used until the end of the cycle. With repeated experience, you can start using Clenbuterol immediately at 40 mcg in the morning + 40 mcg in the evening, or if you are very sensitive to Clenbuterol, you can shorten the pyramid like this:
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Monday = 20 mcg in the morning + 20 mcg in the afternoon
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Tuesday = 30 mcg in the morning + 30 mcg in the afternoon
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Wednesday = 40 mcg in the morning + 40 mcg in the afternoon
Most of you will achieve the best results at 80 mcg daily, provided you weigh between 70 and 90 kg. That is truly enough. Those of you who weigh more can try using 100 to 120 mcg daily. I would not recommend higher doses, but it is up to each of you which dosing method you choose.
How long should Clenbuterol be used? You have surely heard that only about 3 weeks, because after that its effect significantly decreases and a break is needed before starting again. The fact is that after about 3 weeks, Clenbuterol’s effect decreases in beta-2 receptors in muscles, but not in fat tissue. This means its lipolytic effect persists even after 3 weeks. Therefore, it can be used longer — even 4 to 6 weeks. But you can also use the well-known method: 2 weeks “on” and 2 weeks “off”, or 3 weeks “on” and 2 weeks “off.”
Let’s also mention the possible side effects that may occur when using Clenbuterol:
• Increased blood pressure, increased heart rate, headaches
• Hand tremors and trembling voice (this side effect usually lessens over time)
• Stronger sweating, heat flashes. Clenbuterol increases body temperature by 0.3 to 1°C, and in response the body activates sweating to maintain homeostasis. This effect increases caloric expenditure and thus metabolic rate. This is an indirect fat-burning effect, but it applies only to those in whom body temperature rises sufficiently, as this effect does not occur in everyone. Through increased sweating, Clenbuterol is also attributed with diuretic effects, because a person can lose quite a lot of water during its use — but this effect is only temporary and the body replenishes the water immediately after discontinuation.
• Sleep problems are very common with many users — this is normal for all stimulants, especially Clenbuterol, due to its long half-life. But even this effect usually stabilizes over time, probably due to the gradual decline in Clenbuterol’s overall effect.
• Dry mouth and muscle cramps due to electrolyte imbalance (most often due to high or low potassium levels)
Cardarine (GW501516)
It is a chemical compound that belongs to a group of drugs known as selective PPAR-delta receptor modulators, which is a protein that plays a role in regulating various metabolic processes in the body, such as tissue growth, fat oxidation, blood sugar regulation, and more. This is a substance surrounded by many discussions regarding its real effectiveness for fat burning. Some users claim it works for them, while others say the opposite—that it is completely useless. Therefore, you should carefully consider whether or not to include this substance in your cycle.
Its half-life is 12 to 24 hours, so the daily dose can be taken all at once or divided into 2 doses per day. One of the doses is often taken 30–60 minutes before training to support fat oxidation during exercise. The commonly misused dose for fat-burning effects ranges from 10 to 20 mg per day for a duration of 6–12 weeks.
2. Eight-week cycle using Methandienone, Clenbuterol, and T3
In this cycle, an AAS is already used — specifically Methandienone at a daily dose of 20 mg (10 mg in the morning + 10 mg in the evening). Why? Precisely because of the thyroid hormone T3, which is strongly catabolic. Those of you who roll your eyes at Methandienone being included in a cutting cycle simply do not understand this. If you start using AAS, you must also think about maintaining estrogenic activity. If instead of Methandienone you included Stanozolol, Oxandrolone, Turinabol, or another compound, all of these are substances without estrogenic activity, which, at the same time, by suppressing your own testosterone production, also lower E2 levels in the body below reference values — and that is NOT a desirable effect! Too low E2 in men causes:
A. Dehydration of collagen tissues, worsened tendon elasticity, reduced connective tissue strength — meaning tendons lose elasticity, become dry, less flexible, and the likelihood of injury increases.
B. Lower bone density, increasing the risk of fractures — but this applies only to long-term decreased E2 levels measured in months.
C. Reduced muscle blood flow, worsened anti-inflammatory processes, and impaired recovery of muscle micro-tears — overall much weaker regeneration.
D. Decrease in libido, weaker erections, fatigue, worsened mood, depression, sleep issues, and so on.
E. Significant worsening of cholesterol, increasing cardiovascular risks, etc., and I could continue…
Yes, all of this happens when you take Stanozolol, Oxandrolone, Turinabol, and similar drugs in cutting cycles without simultaneously using an aromatizing compound such as testosterone — or in our case, since this is an oral cycle, Methandienone, because it is the only oral substance capable of creating estrogenic activity! Of course, the best choice would be Methyltestosterone, but today it is almost unavailable on the black market.
Those of you who thought of Oxymetholone — yes, it would still theoretically be a better choice than Stanozolol, Oxandrolone, or Turinabol, but Oxymetholone is also a non-aromatizing substance, meaning it does NOT convert into any form of estrogen. Oxymetholone acts directly at the E2 receptors and creates various effects at different levels — which is something different entirely. Again, I will dare to say that many of you are now shaking your heads because I mentioned Oxymetholone in a cutting cycle — you would be surprised how many competitive bodybuilders use Oxymetholone at the end of prep. Alright, I will not dwell on it. Those of you who want to understand will understand, and those who do not want to understand — put whatever you want into your cycle. It is, after all, your cycle and your decision.
I don’t think I need to write much more about Clenbuterol, because we already “covered” enough about it at the beginning of this article. The only thing I will mention here is that the combined use of T3 and Clenbuterol leads to a strengthening of their effects, even though they have completely different mechanisms of action. What are we talking about? A significantly increased heart rate, a higher risk of arrhythmias, increased oxygen demand of the heart, possible left ventricular hypertrophy (with long-term use), disruption of electrolytes (especially potassium), which leads to muscle cramps and arrhythmias, and so on. What does this mean? In most cases, it is enough to reduce the dose of Clenbuterol ⇒ a maximum daily dose of 60 to 80 mcg.
T3 hormone: T3 is the active thyroid hormone responsible for regulating metabolism, body temperature, and energy production. And that is exactly why it is an interesting substance for cutting cycles, because T3 directly increases daily energy expenditure by a few hundred kcal and increases resting metabolism by 10–15%. During T3 use, one may experience heat waves, heart palpitations, headaches, hand tremors, insomnia, and short-term increased appetite (paradoxically). Many of you have certainly heard that you should not take the T3 hormone, and I want to ask out of curiosity—testosterone is a hormone, isn’t it? And you aren’t afraid of that anymore? It is logical that using T3 will reduce the production of your thyroid gland, but that does NOT mean that the gland will be damaged! We will explain this more in detail. Taking thyroid hormones naturally reduces the level of TRH (a hormone released in the hypothalamus in response to detecting low thyroid hormone levels), which then signals a reduction of TSH (which regulates thyroid activity by stimulating the thyroid gland to produce T3 and T4). As a result, the thyroid gland stops producing and slows down its function, but it never shuts down. After discontinuing T3, thyroid function returns to normal within 1–2 weeks on its own. And even long-term use of T3 and T4 does not chronically suppress the HPT axis (hypothalamic–pituitary–thyroid axis), because this axis is resilient and is never chronically suppressed. I will repeat it once again: the activity of the thyroid gland, even despite using T3, will never be chronically suppressed the way the activity of the testes is during testosterone use. During T3 use, the thyroid gland does NOT get damaged! If some “smart” friend tells you that it does, then please ask him to show you a single known case from the past, let’s say, 20 years—during which the internet and forums have existed—where someone had long-term thyroid problems after using T3. You will not find such a case. Of course, T3 should not be used lightly if you have a family history of thyroid disorders, meaning if your parents, grandparents, siblings, or other close relatives have existing thyroid issues. In such cases, T3 is clearly not for you!**
– T3 leads to increased protein synthesis, which sounds pretty good, right? But at the same time, rapid protein breakdown occurs, and unfortunately the speed of breakdown is higher than the speed of synthesis. So the result is clear—T3 use causes protein breakdown = CATABOLISM. From studies we know that exogenously administered T3 preferentially catabolizes hypertrophied muscle! And that is exactly why it is necessary to use Methandienone together with T3 in this cycle, as I already wrote several paragraphs above.
– During T3 use, one may experience heat waves, heart palpitations, headaches, hand tremors, insomnia, and short-term increased appetite (paradoxically).
T3 has a half-life of roughly 2 to 3 days. Its commonly misused dose is most often 37.5 to 75 mcg per day, and there are even people who take 100 mcg per day, though personally I do not see much point in that. Taking 25 mcg daily makes no sense, because natural production is about 28 mcg per day. Therefore the dose of 37.5 mcg and higher has a justification. It is always good to divide the daily dose into 2 or 3 doses as follows:
- -Daily dose 50 mcg = 2 × 25 mcg
- -Daily dose 75 mcg = 2 × 37.5 mcg or 3 × 25 mcg
You will surely wonder why it is good to divide the daily dose of T3 into 2 or 3 parts when it has a long half-life. There are 2 essential reasons:
- Even though the half-life is long, studies show that after taking T3, rapid pharmacodynamic effects occur (rapid rise in fT3 levels).
- The manifestation of negative effects is significantly higher if the full daily dose is taken at once and much lower if the dose is divided into multiple smaller doses.
For the first experience with T3, it is better to start with a lower dose and gradually increase it as follows:
- Monday = 12.5 mcg in the morning + 12.5 mcg in the afternoon
- Tuesday = the same; if everything is fine, increase the dose
- Wednesday = 25 mcg in the morning + 12.5 mcg in the afternoon
- Thursday = the same; if everything is fine, increase the dose
- Friday = 25 mcg in the morning + 25 mcg in the afternoon, and this dose is maintained for several weeks
For repeated use, you can start immediately with 50 mcg on the first day, then later increase to 62.5 mcg or even to 75 mcg. How long to take T3? It is usually used for 4 to 12 weeks. Everything depends on the manifestation of negative side effects and the individual’s satisfaction with the cycle results.
3. Eight-week cycle using Methandienone, Sibutramine, and T3
This cycle is essentially identical to cycle no. 2, except that Sibutramine is used instead of Clenbuterol. We have already explained above how all of these substances are used and why they are included in the cycles. This cycle is suitable for those who are sensitive to the negative effects caused by Clenbuterol, such as heart palpitations, arrhythmia, hand tremors, and similar issues. It is also more suitable for those who truly struggle with controlling their appetite, which will be suppressed by Sibutramine.
4. Eight-week cycle using Methandienone, Sibutramine, and T3
This is the last oral cycle, in which essentially all substances are used — meaning Clenbuterol, T3, and Sibutramine as well. This cycle significantly increases your chances of losing a large amount of fat, provided your diet is of high quality. Personally, I would rather choose one of the first three cycles and try this one maybe sometime in the future if necessary and if I already had experience with all the substances.
5. Twelve-week cycle using Testosterone, Sibutramine, and T3
And here we have the first cycle in which injectable Testosterone is used instead of Methandienone, for a period of 12 weeks, which alone significantly changes the characteristics of any cutting cycle. Together with it, T3 is used during the first 10 weeks of the cycle and Sibutramine for the full 12 weeks. Assuming a quality diet, this cycle can bring a truly very nice change to your physique. Again, I will not write more about the individual substances, because I discussed them at the beginning of this article. Naturally, HCG is used in the cycle as well as Anastrozole in order to control E2 levels — I have already written about this maybe 10 times, why using HCG and an aromatase inhibitor in the cycle is necessary, so I hope I don’t have to repeat it again.
6. Twelve-week cycle using Testosterone, Sibutramine, T3 and Cardarine
This cycle is based on cycle no. 5, but with Cardarine added as a substance to which I personally assign the least significance. Those of you who have good experience with this substance and were satisfied with its effect regarding fat burning — for you this cycle is perfectly tailored.
7. Twelve-week cycle using Testosterone, Clenbuterol, T3 and Cardarine
In this cycle, Sibutramine is not used and instead we have Clenbuterol. If you are wondering which cycle is better and whether you should choose cycle no. 6 with Sibutramine or this one with Clenbuterol, then you should decide based on your sensitivity to Clenbuterol as such (regarding negative effects). If during the use of Clenbuterol you experience many side effects, then the cycle with Sibutramine will definitely be better for you. At the same time, any cycle using Sibutramine has the advantage that it reduces appetite, which is a big plus.
8. Twelve-week cycle using Testosterone, Clenbuterol, Sibutramine and Cardarine
In this cycle, you do not have T3 — who is this cycle suitable for? Primarily for those who are afraid of using T3 and believe more in the internet chatter of uneducated people than in people who actually understand these things. But it is also suitable for those who are afraid of the catabolic effects of T3 and have experienced problems with losing weight and muscle strength while using T3.
9. Twelve-week cycle using Testosterone, Trenbolone, Clenbuterol, Sibutramine and Cardarine
And now this is my favourite combination and I literally love the sophistication of this cycle. The combined use of Testosterone + Trenbolone will bring an increase in IGF-1 levels (thanks to Testosterone) and at the same time a significant increase in the utilisation of IGF-1 in the body (thanks to Trenbolone). Significantly better utilised IGF-1 will substantially support fat burning! As you may notice, the dose of Trenbolone is low because we are only aiming for better utilisation of elevated IGF-1 levels! You surely noticed that short esters are used in the cycle — propionate and acetate — why? Because we need the full effect of both substances to be as fast as possible. In this cycle, Cardarine has great significance because it is known that Trenbolone makes cardio activity difficult and causes shortness of breath, and Cardarine can significantly eliminate this effect! Sibutramine will ensure reduced appetite and Clenbuterol will increase the fat-burning effect => perfection itself.
10. Twelve-week cycle using Testosterone, Trenbolone, T3, Sibutramine and Cardarine
This cycle is basically identical to the previous ninth cycle, with one change — Clenbuterol is removed and instead T3 is used. How is the cycle different now? T3 is a stronger substance than Clenbuterol, and therefore this cycle should be even a little more effective in terms of fat burning. What I would also note — very few of you know that Trenbolone is actually more anti-catabolic than anabolic! I will not dig deeply into this, because most of you likely would not understand it anyway, since when I wrote articles about it, it didn’t really interest you. Why do I mention it? Because of T3, of course! T3 is a strongly catabolic hormone and Trenbolone is a strongly anti-catabolic hormone, meaning this cycle at the same time has the lowest potential for any loss of muscle mass. So this is one of the most effective cycles in terms of fat burning, eliminating catabolic effects, and even supporting anabolic effects!
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